妊高征_不同程度妊高征早产儿0~6,月体格生长及神经运动的早期预后研究

　　【摘要】目的探讨不同程度的妊高征对早产儿体格生长与神经运动发育的影响。方法2009年1月至2010年12月在中山市博爱医院高危儿随访中心建立档案，母亲有妊高征高危因素的早产儿，分为三组(轻度妊高征组；中度妊高征组；重度妊高征组)。前瞻性的对其进行跟踪随访至纠正月龄6个月，测量身高，体重，头围和智力发育情况。结果①三组间出生时体重、身长、头围比较：轻度妊高征组与中、重度妊高征组差别有统计学意义。②纠正胎龄40周时，3组间身长、头围两个指标均为轻度妊高征组与中重度妊高征组差别有统计学意义。③在纠正6月龄时，三组的体重、身长、头围的差别无统计学差异。④生后纠正胎龄40周时行NBNA评分，不同妊高征程度组间的差别无统计学差异。⑤生后纠正6月龄时行Gesell检查，轻度妊高征组与中重度妊高征组差别有统计学差异。结论不同程度妊高征对早产儿早期的体格发育影响不大，对神经运动发育有影响，轻度影响较小，中重度影响较大。在孕期应严格控制轻度妊高征发展成中重度妊高征，减少对婴儿神经运动发育的影响。
　　【关键词】不同程度;妊高征;早产儿;体格发育;神经运动发育
　　A Study of the Early Physical and Neuralogical Bbehavior Development of 0 to 6 MonthOld PretermInfants with Mothers of Different Degrees of PIHLIN Cuilan, HE Wanyi, WEI Wanjian, SHI Yuqi Child Health Division,Zhongshan Boai Hospital,Zhongshan 528400,China
　　【Abstract】ObjectiveTo explore the influences which the control degrees of pregnancyinduced hypertension syndrome (PIH) exert on the physical and neuralogical behavior development of premature infants MethodsThe files of highrisk infants and of the premature infants with PIH mothers established by the HighRisk Infants Followup Center of Boai Hospital, Zhongshan City from January 2009 to December 2010 were collected According to the the PIH extent they were divided into three groups (mild PIH group; moderate PIH group; severe PIH group and followed up until the corrected age of 6 months, with their physical growth and psychomotor development monitored Results①There were significant differences between the mild and the moderate severe groups in the weight, length and head circumference at birth. ②At the corrected gestational age of 40 weeks, there were significant differences of length and head circumference between the mild and the moderate severe groups. ③At the corrected age of 6 months, there were no significant differences of weight, length and head circumference among the three groups ④At the corrected gestational age of 40 weeks, the Neonatal Behavioral Neurological Assessment (NBNA) was carried out and showed no significant differences among the three groups ⑤At the corrected age of 6 months, Gesell Developmental Examination (GDE) was applied and showed that there were significant differences between the mild and the moderate severe groups.ConclusionVarying degrees of PIH control have little effect on physical development Mild PIH has a slight influence on neuromotor development,but moderate to severe have more So mild PIH should be strictly controlled to develop into severe during pregnancy in order to reduce the impact on neuromotor development.